The validity of Acuros BV and TG-43 for high-dose-rate brachytherapy superficial mold treatments

Brachytherapy. 2017 Nov-Dec;16(6):1280-1288. doi: 10.1016/j.brachy.2017.08.010. Epub 2017 Sep 28.

Abstract

Purpose: The purpose of this work is to validate the Acuros BV dose calculation algorithm for high-dose-rate (HDR) brachytherapy superficial mold treatments in the absence of full scatter conditions and compare this with TG-43 dose calculations. We also investigate the impact of additional back scatter material (bolus) applied above surface molds to the dose distributions under the mold.

Methods and materials: The absorbed dose at various depths was compared for simulations performed using either TG-43 or Acuros BV dose calculations. Parameter variations included treatment area, thickness of the bolus, and surface shape (flat or spherical). Film measurements were carried out in a flat phantom.

Results: Acuros BV calculations and film measurements agreed within 1.5% but were up to 15% lower than TG-43 dose calculations when no bolus was applied above the treatment catheters. The difference in dose at the prescription depth (1 cm below the central catheter) increased with increasing treatment area: 3.3% difference for a 3 × 3.5 cm2 source loading area, 7.4% for 8 × 9 cm2, and 13.4% for 18 × 19 cm2. The dose overestimation of the TG-43 model decreased when bolus was added above the treatment catheters.

Conclusions: The TG-43 dosimetry formalism cannot model surface mold treatments in the absence of full scatter conditions within 5% for loading areas larger than approximately 5 × 5 cm2. The TG-43 model results in an overestimation of the delivered dose, which increases with treatment area. This confirms the need for model-based dose calculation algorithms as discussed in TG-186.

Keywords: Acuros BV; Film dosimetry; HDR brachytherapy; Skin treatment; Surface mold; TG-43.

MeSH terms

  • Algorithms*
  • Brachytherapy / instrumentation*
  • Brachytherapy / methods*
  • Catheters
  • Humans
  • Monte Carlo Method
  • Radiometry / methods
  • Radiotherapy Dosage*
  • Radiotherapy Planning, Computer-Assisted / methods
  • Skin Neoplasms / radiotherapy*