What Urinary Colony Count Indicates a Urinary Tract Infection in Children?

J Pediatr. 2017 Dec:191:259-261.e1. doi: 10.1016/j.jpeds.2017.08.012. Epub 2017 Sep 28.

Abstract

Post-hoc analysis of the Randomized Intervention for Children with Vesicoureteral Reflux study suggests that, in concordance with European guidelines, using bacteriologic criterion of ≥10 000 colony forming units/mL of a single organism does not decrease diagnostic specificity of an urinary tract infection in children aged 2 months to 6 years in a properly collected urine if symptoms/fever and pyuria are present.

Trial registration: ClinicalTrials.gov: NCT00405704.

Keywords: guideline; pyuria; suprapubic aspiration; urinary catheterization; vesicoureteral reflux.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Bacteriuria / diagnosis
  • Bacteriuria / etiology
  • Child
  • Child, Preschool
  • Colony Count, Microbial / standards
  • Female
  • Fever / etiology
  • Humans
  • Infant
  • Male
  • Pyuria / etiology
  • Reference Standards
  • Urinary Tract Infections / complications
  • Urinary Tract Infections / diagnosis*
  • Urinary Tract Infections / microbiology
  • Urinary Tract Infections / urine
  • Urine / microbiology*

Associated data

  • ClinicalTrials.gov/NCT00405704