WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs

Bioinformatics. 2017 Oct 1;33(19):3113-3114. doi: 10.1093/bioinformatics/btx383.

Abstract

Summary: WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of times faster, making it suited for metagenomics studies.

Availability and implementation: OpenMP-parallelized GPL-licensed C ++ code available at https://github.com/soedinglab/wish.

Contact: clovis.galiez@mpibpc.mpg.de or soeding@mpibpc.mpg.de.

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Archaea / virology
  • Bacteria / virology
  • Bacteriophages / genetics*
  • Contig Mapping
  • Metagenomics / methods*
  • Software*