Nanopillar Filters for Surface-Enhanced Raman Spectroscopy

ACS Sens. 2017 Oct 27;2(10):1400-1404. doi: 10.1021/acssensors.7b00499. Epub 2017 Sep 29.

Abstract

We present a simple, robust, and automated molecule extraction technique based on a centrifugal microfluidic platform. Fast and facile extraction of a food adulterant (melamine) from a complex sample medium (milk) on a SERS substrate is demonstrated. The unique characteristic of the detection method is the obtained "filter paper/chromatographic" effect which combines centrifugal force and wetting properties of the SERS substrate. The work addresses issues related to SERS-based detection of analytes in complex media, which is important for realizing next generation SERS platforms applicable for a broad variety of real-life applications.

Keywords: SERS; filtration; melamine; microfluidics; nanopillars; wicking.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Food Contamination / prevention & control*
  • Limit of Detection
  • Microfluidics / instrumentation*
  • Microfluidics / methods
  • Milk / chemistry*
  • Spectrum Analysis, Raman / methods*
  • Surface Properties
  • Triazines / isolation & purification*

Substances

  • Triazines
  • melamine