The role of vaccination in risk mitigation and control of Newcastle disease in poultry

Vaccine. 2017 Oct 20;35(44):5974-5980. doi: 10.1016/j.vaccine.2017.09.008. Epub 2017 Sep 23.

Abstract

Newcastle disease is regarded as one of the most important avian diseases throughout the world and continues to be a threat and economic burden to the poultry industry. With no effective treatment, poultry producers rely primarily on stringent biosecurity and vaccination regimens to control the spread of this devastating disease. This concise review provides an historical perspective of Newcastle disease vaccination and how fundamental research has paved the way for the development of instrumental techniques which are still in use today. Although vaccination programmes have reduced the impact of clinical disease, they have historically been ineffective in controlling the spread of virulent viruses and therefore do not always offer an adequate solution to the world's food security problems. However, the continued development of novel vaccine technology and improved biosecurity measures through education may offer a solution to help reduce the global threat of Newcastle disease on the poultry industry.

Keywords: AAvV-1; APMV-1; Biosecurity; Newcastle disease; Vaccine.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Humans
  • Newcastle Disease / immunology*
  • Newcastle Disease / prevention & control*
  • Newcastle disease virus / immunology*
  • Poultry / immunology*
  • Poultry / virology
  • Poultry Diseases / immunology*
  • Poultry Diseases / prevention & control*
  • Poultry Diseases / virology
  • Risk
  • Vaccination / methods