High temperatures and nephrology: The climate change problem

Nefrologia. 2017 Sep-Oct;37(5):492-500. doi: 10.1016/j.nefro.2016.12.008.
[Article in English, Spanish]

Abstract

It is well known that climate change greatly affects human health, even though there are few studies on renal outcomes. Heat waves have been found to increase cardiovascular and respiratory morbidity and mortality, as well as the risk of acute renal failure and hospitalisation due to renal diseases, with related mortality. Recurrent dehydration in people regularly exposed to high temperatures seems to be resulting in an unrecognised cause of proteinuric chronic kidney disease, the underlying pathophysiological mechanism of which is becoming better understood. However, beyond heat waves and extreme temperatures, there is a seasonal variation in glomerular filtration rate that may contribute to the onset of renal failure and electrolyte disorders during extremely hot periods. Although there are few references in the literature, serum sodium disorders seem to increase. The most vulnerable population to heat-related disease are the elderly, children, chronic patients, bedridden people, disabled people, people living alone or with little social contact, and socioeconomically disadvantaged people.

Keywords: Acute renal failure; Alteraciones electrolíticas; Cambio climático; Chronic kidney disease of unknown aetiology; Climate change; Electrolyte disorders; Enfermedad renal crónica de etiología desconocida; Fracaso renal agudo; Nefrología; Nephrology; Seasonal variations of glomerular filtration rate; Variaciones estacionales del filtrado glomerular.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / physiopathology
  • Body Temperature Regulation / physiology
  • Climate Change*
  • Dehydration / etiology
  • Dehydration / physiopathology
  • Disease Susceptibility
  • Glomerular Filtration Rate
  • Health Services Needs and Demand
  • Heat Exhaustion / etiology
  • Heat Exhaustion / physiopathology
  • Hemodynamics
  • Hot Temperature / adverse effects*
  • Humans
  • Kidney / physiology
  • Kidney Diseases / epidemiology
  • Kidney Diseases / etiology*
  • Models, Biological
  • Risk Factors
  • Seasons
  • Sweating / physiology
  • Water-Electrolyte Imbalance / etiology
  • Water-Electrolyte Imbalance / physiopathology