Recent research advances on Chromobacterium violaceum

Vijay Kothari; Sakshi Sharma; Divya Padia

doi:10.1016/j.apjtm.2017.07.022

Recent research advances on Chromobacterium violaceum

Asian Pac J Trop Med. 2017 Aug;10(8):744-752. doi: 10.1016/j.apjtm.2017.07.022. Epub 2017 Aug 19.

Authors

Vijay Kothari¹, Sakshi Sharma², Divya Padia²

Affiliations

¹ Institute of Science, Nirma University, Ahmedabad 382481, India. Electronic address: vijay.kothari@nirmauni.ac.in.
² Institute of Science, Nirma University, Ahmedabad 382481, India.

PMID: 28942822
DOI: 10.1016/j.apjtm.2017.07.022

Abstract

Chromobacterium violaceum is a gram-negative bacterium, which has been used widely in microbiology labs involved in quorum sensing (QS) research. Among the QS-regulated traits of this bacterium, violacein production has received the maximum attention. Violacein production in this organism, however is not under sole control of QS machinery, and other QS-regulated traits of this bacterium also need to be investigated in better detail. Though not often involved in human infections, this bacterium is being viewed as an emerging pathogen. This review attempts to highlight the recent research advances on C. violaceum, with respect to violacein biosynthesis, development of various applications of this bacterium and its bioactive metabolite violacein, and its pathogenicity.

Keywords: Antibiotic resistance; Chromobacterium violaceum; Emerging pathogen; Quorum sensing; Violacein.

Publication types

Review