Role of essential trace elements in tuberculosis infection: A review article

Indian J Tuberc. 2017 Oct;64(4):246-251. doi: 10.1016/j.ijtb.2017.03.003. Epub 2017 Apr 11.

Abstract

Malnutrition is one of the risk factors in tuberculosis (TB) infection. Mineral levels perturbation is seen in patients with TB. Moreover there are some strategies to starve pathogens of essential metals. Here we decided to conclude association between some essential elements and TB. Copper, calcium and iron are essential for hosts' immune system although calcium and iron are necessary for Mycobacterium tuberculosis vitality. Changing these elements alongside with anti-TB therapy is suggested for better treatment outcomes.

Keywords: Calcium; Copper; Iron; Selenium; Tuberculosis; Zinc.

Publication types

  • Review

MeSH terms

  • Calcium / immunology*
  • Calcium / metabolism
  • Copper / immunology*
  • Copper / metabolism
  • Humans
  • Iron / immunology*
  • Iron / metabolism
  • Malnutrition / complications
  • Selenium / immunology*
  • Selenium / metabolism
  • Trace Elements / immunology
  • Trace Elements / metabolism
  • Tuberculosis / blood
  • Tuberculosis / complications
  • Tuberculosis / drug therapy*
  • Zinc / immunology*
  • Zinc / metabolism

Substances

  • Trace Elements
  • Copper
  • Iron
  • Selenium
  • Zinc
  • Calcium