Noninvasive airway approaches for acute neuromuscular respiratory failure in emergency departments

Tai-Heng Chen; Jong-Hau Hsu; Yuh-Jyh Jong

doi:10.1002/ppul.23693

Noninvasive airway approaches for acute neuromuscular respiratory failure in emergency departments

Pediatr Pulmonol. 2017 Oct;52(10):E55-E57. doi: 10.1002/ppul.23693.

Authors

Tai-Heng Chen^{1

2

3}, Jong-Hau Hsu^{3

4}, Yuh-Jyh Jong^{2

4

5}

Affiliations

¹ Divison of Pediatric Emergency, Department of Emergency, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
² Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
³ Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
⁴ Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
⁵ Department of Biological Science and Technology, Institute of Molecular Medicine and Bioengineering, College of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.

PMID: 28941227
DOI: 10.1002/ppul.23693

Abstract

Emerging evidence advocates for noninvasive ventilation (NIV) combined with mechanical in-exsufflation (MIE) as a first-line approach for acute respiratory failure (ARF) in patients with neuromuscular disorders (NMD). To date, most NIV studies of ARF in NMD patients have been performed in intensive care units or in hospital settings. However, the utility of using combined NIV/MIE in the emergency department (ED) settings is unclear. We report on the implementation of NIV/MIE in two children with type II spinal muscular atrophy who presented to the ED with ARF. This is the first report on the feasibility and efficacy of combining NIV/MIE in ED settings for pediatric NMD patients with ARF.

Keywords: acute respiratory failure; emergency department; mechanical in-exsufflator; neuromuscular disorders; noninvasive ventilation.

Publication types

Case Reports

MeSH terms

Adolescent
Child, Preschool
Emergency Service, Hospital
Female
Humans
Noninvasive Ventilation*
Respiratory Insufficiency / therapy*
Spinal Muscular Atrophies of Childhood / therapy*
Treatment Outcome