[Hepatic myelolipoma: A rare entity, case report and review of the literature]

Ann Pathol. 2017 Oct;37(5):415-419. doi: 10.1016/j.annpat.2017.06.010. Epub 2017 Sep 19.
[Article in French]

Abstract

Hepatic myelolipoma is a rare entity with only 17 cases described in the literature. A 73mm right liver mass was fortuitously discovered in a 55-year-old man. The biopsy showed normal hepatic tissue adjacent to a normal medular like hematopoïetic tissue, showing trilieage hematopoieses, including myeloid cells, erythroid cells and megakaryocytic cells. The diagnosis of hepatic myelolipoma was proposed. This benign tumor was initially described in adrenal gland, which is the most common topography. No malignancy or bleeding complication has been described in its hepatical location. The diagnosis is histological due to non-specific radiological presentation; it allows to avoid a surgical treatment in relation to its excellent prognosis. The etiology is not well established; but some hypotheses are discussed: adrenal or medullar heterotopia, bone marrow embolism, myeloïd metaplasia.

Keywords: Extra-adrenal gland myelolipoma; Extremely rare pseudotumor; Hepatic; Hépatique; Myelolipoma; Myélolipome; Myélolipome extra-surrénalien; Pseudotumeur exceptionnelle.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cell Lineage
  • Diagnosis, Differential
  • Hematopoiesis
  • Humans
  • Incidental Findings
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / etiology
  • Liver Neoplasms / pathology
  • Male
  • Middle Aged
  • Myelolipoma / diagnostic imaging*
  • Myelolipoma / etiology
  • Myelolipoma / pathology
  • Tomography, X-Ray Computed*