Lanostane triterpenoids from cultivated fruiting bodies of the basidiomycete Ganoderma australe

Nat Prod Res. 2018 May;32(9):1044-1049. doi: 10.1080/14786419.2017.1378208. Epub 2017 Sep 20.

Abstract

A new lanostane triterpene (1), together with three known compounds (2-4), were isolated from cultivated fruiting bodies of the basidiomycete Ganoderma australe. The structure was elucidated on the basis of NMR spectroscopic and mass spectrometry data. The olefinic geometry of methyl australate (2) was revised from 20(22)Z to 20(22)E. These compounds (1-4) were different from the lanostanes isolated from mycelial cultures of the same strain source.

Keywords: Ganoderma australe; ganodermataceae; lanostane triterpenes.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Drug Evaluation, Preclinical / methods
  • Fruiting Bodies, Fungal / chemistry*
  • Ganoderma / chemistry*
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Spectrometry, Mass, Electrospray Ionization
  • Triterpenes / chemistry*
  • Triterpenes / pharmacology

Substances

  • Anti-Bacterial Agents
  • Triterpenes