Enterovirus D68-Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy

Abstract

In Italy in 2016, acute flaccid myelitis developed in a woman who had received a hematopoietic stem cell transplant. Enterovirus D68 viral genome was detected in respiratory and cerebrospinal fluid samples, and the viral protein 1 sequence clustered with lineage B3. Immunocompromised adults may be at risk for enterovirus D68-associated neurologic complications.

Keywords: Enterovirus D68; Italy; VP1 sequencing; acute flaccid myelitis; central nervous system infection; human; immunocompromised patient; molecular epidemiology; viruses.