Linkage of the DNA-segment D7S13 (pB79a) with the cystic fibrosis locus

Hum Genet. 1988 Feb;78(2):186-7. doi: 10.1007/BF00278194.

Abstract

A map distance of 2.9 cM between D7S13 (pB79a) and the cystic fibrosis (CF) locus was obtained from the analysis of 13 informative families with a history of CF. This result is based solely on the HindIII restriction fragment length polymorphism (HindIII-RFLP) at D7S13, since the interpretation of the MspI-RFLP at this locus was found to be unreliable.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cystic Fibrosis / genetics*
  • DNA / genetics*
  • Genetic Linkage*
  • Genetic Markers*
  • Humans
  • Polymorphism, Restriction Fragment Length

Substances

  • Genetic Markers
  • DNA