Impact of spinal rod stiffness on porcine lumbar biomechanics: Finite element model validation and parametric study

Proc Inst Mech Eng H. 2017 Dec;231(12):1071-1080. doi: 10.1177/0954411917732596. Epub 2017 Sep 19.

Abstract

A three-dimensional finite element model of the porcine lumbar spine (L1-L6) was used to assess the effect of spinal rod stiffness on lumbar biomechanics. The model was validated through a comparison with in vitro measurements performed on six porcine spine specimens. The validation metrics employed included intervertebral rotations and the nucleus pressure in the first instrumented intervertebral disc. The numerical results obtained suggest that rod stiffness values as low as 0.1 GPa are required to reduce the mobility gradient between the adjacent and instrumented segments and the nucleus pressures across the porcine lumbar spine significantly. Stiffness variations above this threshold value have no significant effect on spine biomechanics. For such low-stiffness rods, intervertebral rotations in the instrumented zone must be monitored closely in order to guarantee solid fusion. Looking ahead, the proposed model will serve to examine the transverse process hooks and variable stiffness rods in order to further smooth the transition between the adjacent and instrumented segments, while preserving the stability of the instrumented zone, which is needed for fusion.

Keywords: Adjacent segment disease; finite element modelling; porcine lumbar spine; spinal fusion.

Publication types

  • Validation Study

MeSH terms

  • Animals
  • Biomechanical Phenomena
  • Finite Element Analysis*
  • Lumbar Vertebrae* / anatomy & histology
  • Lumbar Vertebrae* / physiology
  • Mechanical Phenomena*
  • Models, Anatomic
  • Pressure
  • Spinal Cord* / anatomy & histology
  • Spinal Cord* / physiology
  • Swine
  • Weight-Bearing