Abstract
The novel 63,558-bp plasmid pSA-01, which harbors nine antibiotic resistance genes, including cfr, erm(C), tet(L), erm(T), aadD, fosD, fexB, aacA-aphD, and erm(B), was characterized in Staphylococcus arlettae strain SA-01, isolated from a chicken farm in China. The colocation of cfr and fosD genes was detected for the first time in an S. arlettae plasmid. The detection of two IS431-mediated circular forms containing resistance genes in SA-01 suggested that IS431 may facilitate dissemination of antibiotic resistance genes.
Keywords:
IS431; Staphylococcus arlettae; cfr; circular form; fosD.
Copyright © 2017 American Society for Microbiology.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Bacterial Agents / pharmacology*
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Bacterial Proteins / genetics*
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Bacterial Proteins / metabolism
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Chickens
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China / epidemiology
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Drug Resistance, Multiple, Bacterial / genetics*
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Farms
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Fosfomycin / pharmacology*
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High-Throughput Nucleotide Sequencing
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Microbial Sensitivity Tests
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Plasmids / chemistry*
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Plasmids / metabolism
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Poultry Diseases / epidemiology
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Poultry Diseases / microbiology
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology
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Staphylococcal Infections / veterinary*
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Staphylococcus / drug effects
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Staphylococcus / genetics*
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Staphylococcus / isolation & purification
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Staphylococcus / metabolism
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Fosfomycin