Living-Donor Liver Transplantation for Budd-Chiari Syndrome: Case Series

Transplant Proc. 2017 Oct;49(8):1841-1847. doi: 10.1016/j.transproceed.2017.04.028.

Abstract

Background: Venous reconstruction in living-donor liver transplantation for Budd-Chiari syndrome (BCS) has challenges because the grafts from living donors lack vena cava, and hepatic venous anastomosis must be performed on an already-thrombosed and/or stenosed inferior vena cava. Several techniques are described to overcome this problem, and we represent our experience with 22 patients.

Methods: Medical recordings of 22 patients were retrospectively collected, and disease-specific data as well as recordings about surgical technique were analyzed.

Results: Creation of a wide, triangular de novo orifice was the main method used for venous drainage, which was used in 19 patients. The remaining 3 patients had totally thrombosed vena cava; thus, direct anastomosis to the supra-hepatic portion of the vena cava was used in 2 patients and an anastomosis to the right atrium was used in 1 patient.

Conclusions: Venous reconstruction in BCS can be achieved without the use of patch-plasty, and the inferior vena cava can be safely resected in selected patients. Living-donor liver transplantation is a feasible option for the treatment of BCS, considering the scarcity of cavaderic donors.

MeSH terms

  • Adolescent
  • Adult
  • Budd-Chiari Syndrome / surgery*
  • Child
  • Child, Preschool
  • Constriction, Pathologic / surgery
  • Female
  • Hepatic Veins / surgery
  • Humans
  • Liver Transplantation / methods*
  • Living Donors*
  • Male
  • Middle Aged
  • Plastic Surgery Procedures / methods
  • Retrospective Studies
  • Vascular Surgical Procedures / methods
  • Vena Cava, Inferior / surgery
  • Young Adult