Abstract
The enantioselective intermolecular gold(I)-catalyzed [2+2] cycloaddition of terminal alkynes and alkenes has been achieved using non-C2-chiral Josiphos digold(I) complexes as catalysts, by the formation of the monocationic complex. This new approach has been applied to the enantioselective total synthesis of rumphellaone A.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Cycloaddition Reaction
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Cyclobutanes / chemical synthesis*
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Cyclobutanes / chemistry
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Gold / chemistry*
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Molecular Structure
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Sesterterpenes / chemical synthesis*
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Sesterterpenes / chemistry
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Stereoisomerism
Substances
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Cyclobutanes
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Sesterterpenes
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rumphellaone A
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Gold