Delayed cord clamping and cord gas analysis at birth

Acta Obstet Gynecol Scand. 2018 Jan;97(1):7-12. doi: 10.1111/aogs.13233. Epub 2017 Nov 1.

Abstract

Delayed cord clamping for at least 60 s in both term and preterm babies is a major recent change in clinical care. Delayed cord clamping has several effects on other possible interventions. One of these is the effect of delayed cord clamping on umbilical artery gas analysis. When indicated, umbilical artery gas analysis can safely be done either with early cord clamping or, probably most of the times it is necessary, during delayed cord clamping with the cord still unclamped. Paired blood samples (one from the umbilical artery and one from the umbilical vein) can be taken from the pulsating and unclamped cord, immediately after birth, during delayed cord clamping, without any effect on either the accuracy of umbilical artery gas analysis or the transfusion of blood through delayed cord clamping. Umbilical artery gas analysis should instead not be done after delayed cord clamping, since delayed cord clamping alters several acid-based parameters and lactate values.

Keywords: Delayed cord clamping; cord gas analysis; umbilical cord.

MeSH terms

  • Adult
  • Blood Gas Analysis / methods*
  • Constriction
  • Delivery, Obstetric / methods*
  • Female
  • Fetal Blood
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Premature Birth / physiopathology
  • Term Birth / physiology
  • Time Factors
  • Umbilical Arteries*
  • Umbilical Cord / surgery*
  • Umbilical Veins*
  • Vascular Surgical Procedures / methods*