[Classic psychedelic drugs and their potential therapeutic effect]

Ugeskr Laeger. 2017 Sep 11;179(37):V01170005.
[Article in Danish]

Abstract

Over the past decade we have witnessed a renewed scientific interest in the classic hallucinogens (psychedelic drugs). These are substances which exert their effects by an agonist action on the 5-HT2A receptors. The purpose of this paper is to provide a short review and discussion of the psychedelic drugs, their safety profile and their potential antidepressive, anxiolytic and antiaddictive effects. The article primarily focusses on the most recent clinical trials.

Publication types

  • Review

MeSH terms

  • Anti-Anxiety Agents / pharmacology
  • Anti-Anxiety Agents / therapeutic use*
  • Antidepressive Agents / pharmacology
  • Antidepressive Agents / therapeutic use*
  • Anxiety / drug therapy
  • Cluster Headache / drug therapy
  • Depression / drug therapy
  • Hallucinogens / pharmacology
  • Hallucinogens / therapeutic use*
  • Humans
  • Lysergic Acid Diethylamide / pharmacology
  • Lysergic Acid Diethylamide / therapeutic use*
  • Obsessive-Compulsive Disorder / drug therapy
  • Psilocybin / pharmacology
  • Psilocybin / therapeutic use*
  • Receptor, Serotonin, 5-HT2A / drug effects
  • Substance-Related Disorders / drug therapy

Substances

  • Anti-Anxiety Agents
  • Antidepressive Agents
  • Hallucinogens
  • Receptor, Serotonin, 5-HT2A
  • Psilocybin
  • Lysergic Acid Diethylamide