The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies

Mol Ther Nucleic Acids. 2017 Sep 15:8:558-563. doi: 10.1016/j.omtn.2017.08.005. Epub 2017 Aug 12.

Authors

Xiaoyu Chen¹, Jin Liu¹, Josephine M Janssen¹, Manuel A F V Gonçalves²

Affiliations

¹ Department of Molecular Cell Biology, Leiden University Medical Centre, Einthovenweg 20, 2333 ZC Leiden, the Netherlands.
² Department of Molecular Cell Biology, Leiden University Medical Centre, Einthovenweg 20, 2333 ZC Leiden, the Netherlands. Electronic address: m.f.v.goncalves@lumc.nl.

No abstract available

Publication types

Letter