A computerized test for the assessment of mild cognitive impairment subtypes in sentence processing

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2018 Nov;25(6):829-851. doi: 10.1080/13825585.2017.1377679. Epub 2017 Sep 15.

Abstract

This study examines thesentence processing ability of mild cognitive impairment (MCI) subtypes. In addition to standard MCI neuropsychological tests, an experimental approach was applied to assess language. 133 people (93 MCI/40 controls) participated in novel computerized sentence processing tasks. Results presented statistically significant differences between MCI/controls andMCI subtypes (ANOVA):(a) duration F(2,92) = 19.259,p < .001) in sentence construction; (b) correct answers (F(2, 89) = 8.560,p < .001) and duration (F2,89) = 15.525,p < .001)in text comprehension; (c) correct answers (F(2, 92) = 8.975,p < .001) andduration (F(2, 92) = 4.360,p = .016) in metaphoric sentences comprehension; (d) correct answers (F(2, 92) = 12.836,p < .001) andduration (F(2, 92) = 10.974,p < .001) in verb form generation. Subtle changes in MCIsubtypes could affect sentence processing and provide useful information for cognitive decline risk estimation and screening purposes.

Keywords: MCI; aging; computerized assessment; linguistics; screening battery.

MeSH terms

  • Aged
  • Amnesia / diagnosis
  • Cognitive Dysfunction / diagnosis*
  • Comprehension*
  • Diagnosis, Computer-Assisted*
  • Female
  • Humans
  • Language*
  • Male
  • Neuropsychological Tests*
  • Pilot Projects
  • Reproducibility of Results