Objective: To analyze the curative effect of AngioJet mechanical thrombus aspiration combined with catheter directed thrombolysis (CDT) on acute lower extremity deep vein thrombosis (LEDVT). Methods: The clinical data of 20 cases of acute LEDVT treated by AngioJet combined with CDT were analyzed. The inferior vena cava filter was implanted preoperatively, and then the thrombolysis was performed by using AngioJet. The thrombolytic catheter was placed for CDT treatment, and the thrombolysis was evaluated by review angiography. Results: All cases were successfully punctured and catheterized. The suction time was (235±75) seconds. The usage of urokinase was (180±90)*10(4) U. The differences before and after thrombolysis of ipsilateral and contralateral thigh circumference were (8.3±1.5) cm and (2.5±1.0) cm, respectively. The differences before and after thrombolysis of the ipsilateral and contralateral calf circumference were (2.4±1.0)cm and (1.5±0.7) cm, respectively. All of which had statistical significant (P<0.01). Conclusion: AngioJet mechanical thrombus aspiration system is a novel and safe method for the treatment of acute LEDVT. When used in conjunction with CDT, its advantages was more significant.
目的： 应用AngioJet机械性血栓抽吸系统联合导管接触性溶栓(CDT)治疗急性下肢深静脉血栓形成(DVT)的疗效分析。 方法： 分析苏州大学附属第二医院血管外科中心使用AngioJet联合CDT治疗20例急性下肢DVT的临床病例资料，术前植入下腔静脉滤器，使用AngioJet进行碎吸栓，留置溶栓导管行CDT治疗，复查造影评价血栓溶解情况。 结果： 所有病例均成功穿刺并置管，抽吸时间(235±75)s，尿激酶(180±90)万U，溶栓导管留置(1.7±0.8)d，溶栓前后患健侧大腿周径差为(8.3±1.5)cm、(2.5±1.0)cm，溶栓前后患健侧小腿周径差为(2.4±1.0)cm、(1.5±0.7)cm，差异均有统计学意义。 结论： AngioJet机械性血栓抽吸系统是一种新颖的、安全有效的治疗急性中央型及混合型DVT的有效方法，与CDT配合使用时，其优点表现更加显著。.
Keywords: AngioJet; Catheter thrombolysis; Lower extremity deep vein thrombosis; Mechanical thrombosis.