A new dihydrochalcone glycoside from the stems of Homalium stenophyllum

Nat Prod Res. 2018 Apr;32(8):953-958. doi: 10.1080/14786419.2017.1374268. Epub 2017 Sep 14.

Abstract

A new dihydrochalcone glycoside, phloretin-4-O-β-D-glucopyranoside (1), together with seven known flavonoids (2-8), were isolated from the stems of Homalium stenophyllum. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the literature. The known compounds (2-8) were isolated from the genus Homalium for the first time. All compounds were evaluated for their antibacterial activities against six pathogenic bacteria in vitro.

Keywords: Homalium stenophyllum; antibacterial activities; dihydrochalcone glycoside; phloretin-4-O-β-D-glucopyranoside.

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Chalcones / chemistry*
  • Flavonoids / chemistry
  • Glycosides / chemistry*
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Plant Stems / chemistry
  • Salicaceae / chemistry*

Substances

  • Anti-Bacterial Agents
  • Chalcones
  • Flavonoids
  • Glycosides