[Chemical constituents from Barringtonia racemosa]

Zhongguo Zhong Yao Za Zhi. 2016 Jul;41(13):2460-2465. doi: 10.4268/cjcmm20161315.
[Article in Chinese]

Abstract

To investigate the chemical constituents from Barringtonia racemosa, twelve compounds were isolated by chromatography methods and identified as 3β-p-E-coumaroymaslinic acid (1), cis-careaborin (2), careaborin (3), maslinic acid (4), 2α, 3β, 19α-trihydroxyolean-12-ene-24, 28-dioic acid (5), 3β-p-Z-coumaroylcorosolic acid (6), corosolic acid (7), 1α, 2α, 3β, 19α-tetrahydroxyurs-12-en-28-oic acid (8), 19α-hydroxyl ursolic acid (9), 3α, 19α-dihydroxyurs-12-en-24, 28-dioic acid (10), tormentic acid (11), 3-hydroxy-7, 22-dien-ergosterol(12) by the NMR and MS data analysis. Among them, compounds 1-4,7-12 were obtained from the genus Barringtonia for the first time. All the compounds didn't show nocytotoxic activity against MCF-7 and A549 cell lines (IC₅₀>50 mg•L⁻¹).

Keywords: Barringtonia racemosa; chemical constituents; cytotoxicity; triterpenes.

MeSH terms

  • Barringtonia / chemistry*
  • Molecular Structure
  • Phytochemicals / analysis
  • Plant Extracts / analysis*
  • Triterpenes / analysis*

Substances

  • Phytochemicals
  • Plant Extracts
  • Triterpenes
  • careaborin