Incidental Detection of Hepatocellular Carcinoma on 68Ga-Labeled Prostate-Specific Membrane Antigen PET/CT

Clin Nucl Med. 2017 Nov;42(11):881-884. doi: 10.1097/RLU.0000000000001832.

Abstract

A 66-year-old man with history of prostate carcinoma underwent Ga-labeled prostate-specific membrane antigen PET/CT for surveillance of rising prostate-specific antigen. Intense tracer uptake was noted in segments 2, 7, and 8 of the liver. The lesions were not FDG avid on F-FDG PET/CT. Further characterization with magnetic resonance cholangiopancreatography with Gd-EOB (Primovist) contrast revealed ill-defined arterially enhancing lesions with central washout in the venous phase. CT-guided core biopsy was performed, and histopathology confirmed well-differentiated hepatocellular carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Hepatocellular / diagnostic imaging*
  • Carcinoma, Hepatocellular / pathology
  • Gallium Radioisotopes*
  • Humans
  • Incidental Findings*
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / pathology
  • Male
  • Middle Aged
  • Positron Emission Tomography Computed Tomography*
  • Prostate-Specific Antigen*

Substances

  • Gallium Radioisotopes
  • Gallium-68
  • Prostate-Specific Antigen