Paracoccidioidomycosis (PCM) is a systemic mycosis that represents an important public health problem in Latin America due to its life-threatening character. It is considered occupational disease of agricultural workers. In this report, we present a rare and serious case of the acute form of the disease in a 40-year-old man with no history of contact with the rural environment. Diagnosis was made through cervical lymph node biopsy, and treatment was performed with antifungal drugs, which produced effective results. A literature review was conducted with discussion of clinical, pathophysiological and therapeutic aspects of PCM.
Keywords: Differential diagnosis; Lymph node excision; Mycoses; Otolaryngology; Paracoccidioidomycosis.