Extrapolating meaning from local field potential recordings

J Integr Neurosci. 2017;16(1):107-126. doi: 10.3233/JIN-170011.

Abstract

Local field potentials (LFP) reflect the spatially weighted low-frequency activity nearest to a recording electrode. LFP recording is a window to a wide range of cellular activities and has gained increasing attention over recent years. We here review major conceptual issues related to LFP with the goal of creating a resource for non-experts considering implementing LFP into their research. We discuss the cellular activity that constitutes the local field potential; recording techniques, including recommendations and limitations; approaches to analysis of LFP data (with focus on power-banded analyses); and finally we discuss reports of the successful use of LFP in clinical applications.

Keywords: LFP; electrophysiology; extracellular; field potentials; local field potentials.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Microelectrodes*
  • Nervous System Physiological Phenomena
  • Neurons / physiology*
  • Signal Processing, Computer-Assisted