Genomics of Helicobacter pylori

Helicobacter. 2017 Sep:22 Suppl 1. doi: 10.1111/hel.12409.

Abstract

As Helicobacter pylori infects half the world's population and displays an extensive intraspecies diversity, genomics is a powerful tool to understand evolution and disease, to identify factors that confer higher risk of severe sequelae, and to find new approaches for therapy both among bacterial and host targets. In line with these objectives, this review article summarizes the major findings in Helicobacter genomics in papers published between April 2016 and March 2017.

Keywords: diversity; genome; methylation; pathogenicity island; sequencing.

Publication types

  • Review

MeSH terms

  • Evolution, Molecular
  • Genes, Bacterial*
  • Genome, Bacterial*
  • Genomics
  • Helicobacter pylori / classification
  • Helicobacter pylori / genetics*
  • Helicobacter pylori / pathogenicity
  • Host-Pathogen Interactions
  • Humans