Candida auris: An emerging multidrug-resistant pathogen

Int J Infect Dis. 2017 Oct:63:95-98. doi: 10.1016/j.ijid.2017.08.017. Epub 2017 Sep 6.

Abstract

Candida aurisis an emerging multidrug-resistant pathogen that can be difficult to identify using traditional biochemical methods. C. auris is capable of causing invasive fungal infections, particularly among hospitalized patients with significant medical comorbidities. Echinocandins are the empiric drugs of choice for C. auris, although not all isolates are susceptible and resistance may develop on therapy. Nosocomial C. auris outbreaks have been reported in a number of countries and aggressive infection control measures are paramount to stopping transmission.

Keywords: Candida auris; Healthcare-associated; Infection control; Multidrug-resistance; Outbreak.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candida / drug effects*
  • Candida / isolation & purification*
  • Candidiasis / drug therapy
  • Communicable Diseases, Emerging / microbiology*
  • Cross Infection / drug therapy
  • Dose-Response Relationship, Drug
  • Drug Resistance, Multiple, Fungal*
  • Echinocandins / therapeutic use
  • Humans
  • Infection Control
  • Microbial Sensitivity Tests

Substances

  • Antifungal Agents
  • Echinocandins