Identification of HLA-B*58:01:21, a novel allele in a Korean individual

HLA. 2017 Dec;90(6):371-372. doi: 10.1111/tan.13144. Epub 2017 Sep 28.

Abstract

B*58:01:21 has a single nucleotide change, c.264A>G (ACA→ACG at codon 88) compared with B*58:01:01:01.

Keywords: HLA-B*58:01:21; human leukocyte antigen; novel allele; sequence-based typing.

MeSH terms

  • Alleles*
  • Asian People
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • Gene Expression
  • Genotype
  • HLA-A11 Antigen / genetics*
  • HLA-A11 Antigen / immunology
  • HLA-B Antigens
  • Hematopoietic Stem Cell Transplantation
  • Histocompatibility Testing
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Tissue Donors

Substances

  • Codon
  • HLA-A11 Antigen
  • HLA-B Antigens
  • HLA-B*58:01 antigen