The Study on the Correlation Between Six Kinds of Mineral Elements and Diabetes

Biol Trace Elem Res. 2018 Jun;183(2):226-232. doi: 10.1007/s12011-017-1136-6. Epub 2017 Sep 7.

Abstract

The study aimed to explore the relationship of six kinds of mineral elements and diabetes among adults in northeast China. A cross-sectional survey was conducted in Jilin Province, northeast China. A total of 366 males and 204 females aged 18 ~ 77 years from Jingyu town, Dongliao town, and Changling town were included using a multistage stratified random cluster sampling design. Data was obtained from face to face interview, physical examination, and laboratory measurement. We defined the normal people (3.9 ~ 6.0 mmol/L), impaired fasting glucose (IFG) individuals (6.1 ~ 6.9 mmol/L), and diabetes mellitus (DM) (> 7.0 mmol/L) according to the WHO diagnostic criteria. Kruskal-Wallis test, Spearman rank correlation, as well as binary logistic regression were used to analyze influencing factors. lg(Cu/Zn)was correlated with DM (OR 8.390; 95% CI of OR 1.272-55.347). The specific mineral elements such as Zn, Ca, as well as Cu/Zn ratio may be the potential risk factors for diabetes. So, the supplement or reduction of these elements is supposed to be told to IFG to prevent or delay the occurrence of diabetes or DM to avoid its complication.

Keywords: Cross-sectional study; Diabetes; Mineral elements; North China.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blood Glucose / metabolism*
  • Calcium / blood
  • China
  • Copper / blood
  • Cross-Sectional Studies
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / metabolism*
  • Fasting / blood
  • Female
  • Glucose Intolerance / metabolism
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Young Adult
  • Zinc / blood

Substances

  • Blood Glucose
  • Copper
  • Zinc
  • Calcium