Complete genome sequence of the first human parechovirus type 3 isolated in Taiwan

Jenn-Tzong Chang; Chih-Shiang Yang; Bao-Chen Chen; Yao-Shen Chen; Tsung-Hsien Chang

doi:10.1016/j.jcma.2017.07.007

Complete genome sequence of the first human parechovirus type 3 isolated in Taiwan

J Chin Med Assoc. 2017 Nov;80(11):737-739. doi: 10.1016/j.jcma.2017.07.007. Epub 2017 Sep 4.

Authors

Jenn-Tzong Chang¹, Chih-Shiang Yang², Bao-Chen Chen³, Yao-Shen Chen⁴, Tsung-Hsien Chang⁵

Affiliations

¹ Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
² Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
³ Department of Microbiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
⁴ Department of Infectious Diseases, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
⁵ Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC; Department of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan, Taiwan, ROC. Electronic address: changth@vghks.gov.tw.

PMID: 28882730
DOI: 10.1016/j.jcma.2017.07.007

Abstract

The first human parechovirus 3 (HPeV3 VGHKS-2007) in Taiwan was identified from a clinical specimen from a male infant. The entire genome of the HPeV3 isolate was sequenced and compared to known HPeV3 sequences. Genome alignment data showed that HPeV3 VGHKS-2007 shares the highest nucleotide identity, 99%, with the Japanese strain of HPeV3 1361K-162589-Yamagata-2008. All HPeV3 isolates possess at least 97% amino acid identity. The analysis of the genome sequence of HPeV3 VGHKS-2007 will facilitate future investigations of the epidemiology and pathogenicity of HPeV3 infection.

Keywords: Clinical isolate; Genome sequence; Human parechovirus.

MeSH terms

Genome, Viral*
Humans
Infant
Male
Parechovirus / genetics*
Sequence Alignment
Taiwan
Whole Genome Sequencing*