[Research progress of anti-drug resistance in traditional Chinese medicine]

Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(5):813-817. doi: 10.4268/cjcmm20160509.
[Article in Chinese]

Abstract

Bacterial drug resistance has been always the focus of the world. With the abuse of antibiotics and the emerging of "Superbug" in the world, the harm of drug resistance to human beings is more and more serious, with an uncontrollable trend. Today, with the relative lack of antibiotics, people pay more attention to Chinese herbal medicines with a wide range of sources, high security, less toxic side effects and mysterious anti-drug resistance mechanism, hoping to find new ways or new ideas to solve the problem of drug resistance. In recent years, the screening, extracting and isolating of effective drug resistance inhibitors from natural plants and traditional Chinese Medicine, as well as the investigation in mechanism of anti-drug resistance, have become a hot research in the field of medicine. In this paper, we would analyze and summarize the action mechanism of bacterial drug resistance, characteristics and advantages of anti-drug resistance of traditional Chinese medicine, as well as the herbal ingredients with anti-drug resistance effect, hoping to provide certain theoretical basis and research ideas for solving the problem of bacterial drug resistance and developing new green Chinese antibiotics.

Keywords: bacteria; drug resistance; green antibiotics; traditional Chinese medicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacteria / drug effects*
  • Bacteria / genetics
  • Bacterial Infections / drug therapy
  • Bacterial Infections / microbiology*
  • Bacterial Physiological Phenomena
  • Drug Resistance, Bacterial*
  • Drugs, Chinese Herbal / administration & dosage*
  • Humans

Substances

  • Drugs, Chinese Herbal