Phenolic contents, cellular antioxidant activity and antiproliferative capacity of different varieties of oats

Chao Chen; Li Wang; Ren Wang; Xiaohu Luo; Yongfu Li; Juan Li; Yanan Li; Zhengxing Chen

doi:10.1016/j.foodchem.2017.06.104

Phenolic contents, cellular antioxidant activity and antiproliferative capacity of different varieties of oats

Food Chem. 2018 Jan 15:239:260-267. doi: 10.1016/j.foodchem.2017.06.104. Epub 2017 Jun 20.

Authors

Chao Chen¹, Li Wang², Ren Wang¹, Xiaohu Luo¹, Yongfu Li¹, Juan Li¹, Yanan Li¹, Zhengxing Chen³

Affiliations

¹ State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; Collaborative Innovation Center for Food Safety and Quality Control in Jiangsu Province, Wuxi 214122, China.
² State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; Collaborative Innovation Center for Food Safety and Quality Control in Jiangsu Province, Wuxi 214122, China. Electronic address: legend0318@hotmail.com.
³ State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; Collaborative Innovation Center for Food Safety and Quality Control in Jiangsu Province, Wuxi 214122, China. Electronic address: zxchen_2008@126.com.

PMID: 28873568
DOI: 10.1016/j.foodchem.2017.06.104

Abstract

The objectives of this research were to determine the phenolic contents, oxygen radical absorbance capacities (ORAC), cellular antioxidant activities (CAA), and antiproliferative capacities of nine oat varieties and four brans in China. Of all varieties, Longyan 3 and Beiyan 1 exhibited the highest total avenanthramides (146.94±7.31 and 120.95±6.66µg/g, respectively) and ORAC values (21.03±0.56 and 21.18±1.45µM Trolox/g, respectively), while Shaotong exhibited the highest total phenolic acids (143.52±9.42µg/g) and CAA values (33.38±1.74µM quercetin/100g). The EC₅₀ of antiproliferative capacities ranged from 167.31±6.42 to 233.42±21.31mg/mL, with the lowest in Beixiao 8 while the highest in Jinyan 8. ORAC values correlated with avenanthramides while CAA values correlated with phenolic acids. Moreover, phenolic contents, antioxidant properties, and antiproliferative capacities of oat brans was higher than that of corresponding whole oats in most cases.

Keywords: Antiproliferative capacity; Avenanthramide; Cellular antioxidant activity; Oat; Phenolic acid.

MeSH terms

Antioxidants
Avena*
Cell Proliferation
Humans
Phenols
Plant Extracts

Substances

Antioxidants
Phenols
Plant Extracts