Abstract
Parkinsonism (PD) is the clinical syndrome of bradykinesia combined with rigidity and/or tremor at rest. These are the defining characteristics of PD, but they are present in many other diseases of the brain. The most frequent differential diagnosis of PD are the atypical parkinsonian syndromes and the conditions presenting with mainly lower body parkinsonism. Discrimination between these can be challenging, especially at early stages of the disease, but nevertheless of utmost importance, because treatment and prognosis vary. Diagnoses are clinical, as disease-specific biomarkers are still lacking.
MeSH terms
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Diagnosis, Differential
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Humans
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Lewy Body Disease / diagnosis
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Lewy Body Disease / diagnostic imaging
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Multiple System Atrophy / diagnosis
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Multiple System Atrophy / diagnostic imaging
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Parkinson Disease / diagnosis
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Parkinson Disease / diagnostic imaging
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Parkinson Disease, Secondary / diagnosis
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Parkinson Disease, Secondary / diagnostic imaging
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Parkinsonian Disorders / diagnosis*
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Parkinsonian Disorders / diagnostic imaging
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Supranuclear Palsy, Progressive / diagnosis
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Supranuclear Palsy, Progressive / diagnostic imaging
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Tomography, Emission-Computed, Single-Photon
Supplementary concepts
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Parkinson Disease, Familial, Type 1