Low modulus and bioactive Ti/α-TCP/Ti-mesh composite prepared by spark plasma sintering

Yu Guo; Yanni Tan; Yong Liu; Shifeng Liu; Rui Zhou; Hanchun Tang

doi:10.1016/j.msec.2017.05.014

Low modulus and bioactive Ti/α-TCP/Ti-mesh composite prepared by spark plasma sintering

Mater Sci Eng C Mater Biol Appl. 2017 Nov 1:80:197-206. doi: 10.1016/j.msec.2017.05.014. Epub 2017 May 12.

Authors

Yu Guo¹, Yanni Tan², Yong Liu³, Shifeng Liu⁴, Rui Zhou¹, Hanchun Tang¹

Affiliations

¹ State Key Laboratory of Powder Metallurgy, Central South University, Changsha, Hunan 410083, PR China.
² State Key Laboratory of Powder Metallurgy, Central South University, Changsha, Hunan 410083, PR China. Electronic address: tanyanni@csu.edu.cn.
³ State Key Laboratory of Powder Metallurgy, Central South University, Changsha, Hunan 410083, PR China. Electronic address: yonliu@csu.edu.cn.
⁴ School of Metallurgical Engineering, Xi'an University of Architecture and Technology, Xi'an, Shaanxi 710055, PR China; State Key Laboratory of Powder Metallurgy, Central South University, Changsha, Hunan 410083, PR China.

PMID: 28866157
DOI: 10.1016/j.msec.2017.05.014

Abstract

A titanium mesh scaffold composite filled with Ti/α-TCP particles was prepared by spark plasma sintering (SPS). The microstructures and interfacial reactions of the composites were investigated by scanning electron microscopy (SEM), Energy Dispersive Spectroscopy (EDS) and X-ray diffraction (XRD) analyses. The compressive strength and elastic modulus were also measured. In vitro bioactivity and biocompatibility was evaluated by using simulated body fluid and cells culture, respectively. After high temperature sintering, Ti oxides, Ti_xP_y and CaTiO₃ were formed. The formation of Ti oxides and Ti_xP_y were resulted from the diffusion of O and P elements from α-TCP to Ti. CaTiO₃ was the reaction product of Ti and α-TCP. The composite of 70Ti/α-TCP incorporated with Ti mesh showed a high compressive strength of 589MPa and a low compressive modulus of 30GPa. The bioactivity test showed the formation of a thick apatite layer on the composite and well-spread cells attachment. A good combination of mechanical properties and bioactivity indicated a high potential application of Ti/α-TCP/Ti-mesh composite for orthopedic implants.

Keywords: Composites; Mesh; Spark plasma sintering; Titanium; α-Tricalcium phosphate.

MeSH terms

Apatites
Calcium Phosphates
Compressive Strength
Materials Testing*
Microscopy, Electron, Scanning
Prostheses and Implants
X-Ray Diffraction

Substances

Apatites
Calcium Phosphates