Near-Infrared Intraoperative Imaging Can Successfully Identify Malignant Pleural Mesothelioma After Neoadjuvant Chemotherapy

Mol Imaging. 2017 Jan-Dec:16:1536012117723785. doi: 10.1177/1536012117723785.

Abstract

Malignant pleural mesothelioma is a deadly disease. Complete surgical resection provides patients with the best opportunity for long-term survival. Unfortunately, identification of disease during resection can be challenging. In this report, we describe successful intraoperative utilization of the near-infrared imaging agent, indocyanine green, to help the surgeon identify malignant disease in a patient with malignant pleural mesothelioma who had previously received neoadjuvant chemotherapy. This technology may ultimately enhance the thoracic surgeon's ability to identify small disease deposits at the time of resection.

Keywords: inflammation; intraoperative imaging; malignant pleural mesothelioma; surgery.

MeSH terms

  • Female
  • Humans
  • Inflammation
  • Lung Neoplasms / immunology
  • Lung Neoplasms / therapy*
  • Male
  • Mesothelioma / immunology
  • Mesothelioma / therapy*
  • Mesothelioma, Malignant
  • Neoadjuvant Therapy / methods*