Effect of Pectin Gel Particles on Endotoxemia Induced by Restraint Stress in Mice

N M Paderin; A S Polugrudov; D S Khramova; S V Popov

doi:10.1007/s10517-017-3818-7

Effect of Pectin Gel Particles on Endotoxemia Induced by Restraint Stress in Mice

Bull Exp Biol Med. 2017 Aug;163(4):419-421. doi: 10.1007/s10517-017-3818-7. Epub 2017 Aug 29.

Authors

N M Paderin¹, A S Polugrudov², D S Khramova², S V Popov²

Affiliations

¹ Institute of Physiology, Komi Research Center, Ural Division of the Russian Academy of Sciences, Syktyvkar, Russia. paderin_nm@mail.ru.
² Institute of Physiology, Komi Research Center, Ural Division of the Russian Academy of Sciences, Syktyvkar, Russia.

PMID: 28853093
DOI: 10.1007/s10517-017-3818-7

Abstract

We studied the effect of pectin gel particles on endotoxemia in mice induced by restraint stress. It was shown that the concentration of LPS in mouse blood increased during restraint stress, which was associated with memory impairment. Pectin gel particles prevented the development of stress-induced endotoxemia and memory impairment in mice.

Keywords: endotoxemia; pectin gel particles; restraint stress.

MeSH terms

Animals
Antioxidants / metabolism
Catalase / blood
Catalase / metabolism
Endotoxemia / drug therapy
Endotoxemia / metabolism*
Male
Malondialdehyde / blood
Malondialdehyde / metabolism
Mice
Pectins / chemistry*
Rats, Wistar
Stress, Physiological / drug effects
Superoxide Dismutase / blood
Superoxide Dismutase / metabolism
Transaminases / blood
Transaminases / metabolism

Substances

Antioxidants
Malondialdehyde
Pectins
Catalase
Superoxide Dismutase
Transaminases