Abstract
Syndecan-1 chondroitin sulfate glycopeptide was synthesized for the first time using the cassette approach. The sequence of glycosylation to form the octasaccharide serine cassette was critical. The glycopeptide was successfully assembled via a 2+ (3 + 3) glycosylation strategy followed by peptide chain elongation.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Chondroitin Sulfates / chemistry*
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Glycopeptides
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Glycosylation
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Heparitin Sulfate
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Molecular Structure
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Proteoglycans
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Syndecan-1
Substances
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Glycopeptides
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Proteoglycans
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Syndecan-1
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Chondroitin Sulfates
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Heparitin Sulfate