Apnea and heart rate detection from tracheal body sounds for the diagnosis of sleep-related breathing disorders

Med Biol Eng Comput. 2018 Apr;56(4):671-681. doi: 10.1007/s11517-017-1706-y. Epub 2017 Aug 29.

Abstract

Sleep apnea is one of the most common sleep disorders. Here, patients suffer from multiple breathing pauses longer than 10 s during the night which are referred to as apneas. The standard method for the diagnosis of sleep apnea is the attended cardiorespiratory polysomnography (PSG). However, this method is expensive and the extensive recording equipment can have a significant impact on sleep quality falsifying the results. To overcome these problems, a comfortable and novel system for sleep monitoring based on the recording of tracheal sounds and movement data is developed. For apnea detection, a unique signal processing method utilizing both signals is introduced. Additionally, an algorithm for extracting the heart rate from body sounds is developed. For validation, ten subjects underwent a full-night PSG testing, using the developed sleep monitor in concurrence. Considering polysomnography as gold standard the developed instrumentation reached a sensitivity of 92.8% and a specificity of 99.7% for apnea detection. Heart rate measured with the proposed method was strongly correlated with heart rate derived from conventional ECG (r 2 = 0.8164). No significant signal losses are reported during the study. In conclusion, we demonstrate a novel approach to reliably and noninvasively detect both apneas and heart rate during sleep.

Keywords: Heart sounds; Monitoring; Respiratory sounds; Sleep apnea.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Electrocardiography
  • Equipment Design
  • Female
  • Heart Rate / physiology*
  • Humans
  • Male
  • Middle Aged
  • Monitoring, Physiologic
  • Polysomnography / methods*
  • Respiratory Sounds / classification*
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted*
  • Sleep Apnea Syndromes / diagnosis*
  • Trachea / physiology