Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications

Drug Discov Today. 2017 Dec;22(12):1825-1834. doi: 10.1016/j.drudis.2017.08.006. Epub 2017 Aug 25.

Abstract

Zinc oxide (ZnO) nanoparticles (NPs) are a promising platform for use in biomedical research, especially given their anticancer and antimicrobial activities. These activities are associated with the ability of ZnO NPs to generate reactive oxygen species (ROS) and induce apoptosis. In addition, ZnO NPs have been successfully exploited as drug carriers for loading and transporting drugs to target sites, thereby reducing unwanted toxicity and off-target effects, and resulting in amplified synergistic effects. Here, we discuss the synthesis and biomedical applications of ZnO NPs.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Nanoparticles* / administration & dosage
  • Nanoparticles* / chemistry
  • Zinc Oxide* / chemistry
  • Zinc Oxide* / pharmacokinetics
  • Zinc Oxide* / pharmacology

Substances

  • Zinc Oxide