Characterization of a stepwise approach in cavotricuspid isthmus ablation for typical atrial flutter: A randomized study comparing three catheters

Pacing Clin Electrophysiol. 2017 Oct;40(10):1052-1058. doi: 10.1111/pace.13170. Epub 2017 Sep 20.

Abstract

Introduction: Our aim was to characterize a stepwise approach in cavotricuspid isthmus ablation for typical atrial flutter in a prospective, noncrossover randomized study.

Methods: One hundred and fifty patients referred for cavotricuspid isthmus (CTI)-dependent atrial flutter ablation were randomized to undergo an ablation with an 8-mm-tip catheter (group 1), a 3.5-mm open irrigation-tip catheter (group 2), and a 3.5-mm open irrigation porous-tip catheter (group 3). A stepwise approach was performed, changing the ablation site from medial to septal aspects of the CTI, in case it was not effective without crossover between catheters.

Results: CTI block was achieved in all the patients using only one catheter. There was a 68% efficacy in group 1, 40% in group 2, and 28% in group 3 to achieve CTI block within 10 minutes (P = 0.001) and 96%, 70%, and 70% in groups 1, 2, and 3, respectively, within 20 minutes (P = 0.002) of radiofrequency ablation. The 8-mm catheter was also faster in fluoroscopy time and CTI block time. There were no differences in efficiency in the both irrigated catheters. There were no significant differences in complications among three catheters.

Conclusions: With this stepwise approach, it is possible to achieve CTI block in all cases, using a single catheter without crossover, with good times of procedure and with a low complication rate. The 8-mm solid catheter is faster than the other irrigated-tip catheters. The 3.5-mm open irrigation porous-tip catheter is as effective and safe as the conventional irrigated-tip catheter.

Keywords: atrial flutter; catheter ablation; irrigated-tip catheter; isthmus block; radiofrequency.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Atrial Flutter / surgery*
  • Catheter Ablation / instrumentation*
  • Catheter Ablation / methods*
  • Catheters
  • Equipment Design
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Tricuspid Valve / surgery*
  • Vena Cava, Inferior / surgery*