Differential Day-Night Outcome to HSV-2 Cutaneous Infection

J Invest Dermatol. 2018 Jan;138(1):233-236. doi: 10.1016/j.jid.2017.07.838. Epub 2017 Aug 24.

Authors

Takamitsu Matsuzawa¹, Yuki Nakamura², Youichi Ogawa¹, Kayoko Ishimaru², Fumi Goshima³, Shinji Shimada¹, Atsuhito Nakao⁴, Tatsuyoshi Kawamura⁵

Affiliations

¹ Department of Dermatology, Faculty of Medicine, University of Yamanashi, Shimokato, Chuo, Yamanashi, Japan.
² Department of Immunology, Faculty of Medicine, University of Yamanashi, Shimokato, Chuo, Yamanashi, Japan.
³ Department of Virology, Nagoya University Graduate School of Medicine, Tsurumai-cho, Showa-ku, Nagoya, Japan.
⁴ Department of Immunology, Faculty of Medicine, University of Yamanashi, Shimokato, Chuo, Yamanashi, Japan; Atopy Research Center, Juntendo University School of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan. Electronic address: anakao@yamanashi.ac.jp.
⁵ Department of Dermatology, Faculty of Medicine, University of Yamanashi, Shimokato, Chuo, Yamanashi, Japan. Electronic address: tkawa@yamanashi.ac.jp.

PMID: 28842321
DOI: 10.1016/j.jid.2017.07.838

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acyclovir / pharmacology
Acyclovir / therapeutic use
Animals
Antiviral Agents / pharmacology
Antiviral Agents / therapeutic use
Circadian Clocks / physiology*
DNA-Binding Proteins / genetics
Disease Models, Animal
Dose-Response Relationship, Drug
Female
Herpes Simplex / mortality
Herpes Simplex / physiopathology*
Herpes Simplex / prevention & control
Herpes Simplex / virology
Herpesvirus 2, Human / isolation & purification
Herpesvirus 2, Human / pathogenicity*
Host Microbial Interactions / physiology*
Humans
Mice
Mice, Inbred C57BL
Mice, Knockout
Nectins / metabolism
Severity of Illness Index
Skin / metabolism
Skin / virology
Survival Rate
Treatment Outcome

Substances

Antiviral Agents
DNA-Binding Proteins
Nectin1 protein, mouse
Nectins
Rag2 protein, mouse
Acyclovir