More evidence that salt increases blood pressure and risk of kidney disease from the Science of Salt: A regularly updated systematic review of salt and health outcomes (April-July 2016)

J Clin Hypertens (Greenwich). 2017 Aug;19(8):813-823. doi: 10.1111/jch.13049.

Abstract

The purpose of this review is to identify, summarize, and critically appraise studies on dietary salt and health outcomes that were published from April to July 2016. The search strategy was adapted from a previous systematic review on dietary salt and health. We have revised our criteria for methodological quality and health outcomes, which are applied to select studies for detailed critical appraisals and written commentary. Overall, 28 studies were identified and are summarized in this review. Four of the 28 studies met criteria for methodological quality and health outcomes and five studies underwent detailed critical appraisals and commentary. Three of these studies found adverse effects of salt on health outcomes (chronic kidney disease and blood pressure) and two were neutral (fracture risk/bone mineral density and cognitive impairment).

Keywords: diet; hypertension; lifestyle modification; nutrition; sodium.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Clinical Studies as Topic
  • Humans
  • Hypertension / chemically induced
  • Hypertension / epidemiology*
  • Nutrition Assessment
  • Renal Insufficiency, Chronic / chemically induced
  • Renal Insufficiency, Chronic / epidemiology*
  • Research Design
  • Sodium Chloride, Dietary / adverse effects*

Substances

  • Sodium Chloride, Dietary