Heart Failure Transitions of Care: A Pharmacist-Led Post-Discharge Pilot Experience

Prog Cardiovasc Dis. 2017 Sep-Oct;60(2):249-258. doi: 10.1016/j.pcad.2017.08.005. Epub 2017 Aug 19.

Abstract

Objective: To perform a pilot evaluation of a pharmacist-led, multidisciplinary transitional care clinic for heart failure (HF) patients.

Background: Transitions of care in HF should include: medication reconciliation, multidisciplinary care, early post-discharge follow-up, and prompt intervention on HF signs and symptoms. We hypothesized that combining these elements with optimization of medications would impact outcomes.

Methods: In the SERIOUS HF Medication Reconciliation Transitional Care Clinic (HF MRTCC), patients were seen by a clinical pharmacist trained in HF. The pharmacist performed medication reconciliation, a basic physical exam, and a HF symptom history. Medications were adjusted by the clinical pharmacist or medical provider. Data were retrospectively collected for a quality improvement evaluation of this novel clinic on medication discrepancies, medications optimized, and 30-day readmissions. Descriptive statistics and paired t-tests were used for medication doses.

Results: All patients (n=135) had a diagnosis of HF, 59% were recently discharged. The mean time from discharge to the clinic appointment was 10±6days, and the 30day all-cause readmission rate was 9%. Medication discrepancies were detected in 53% of patients. Medications were optimized in 70%, most frequently beta blockers, ace inhibitors, and diuretics. In patients with an ejection fraction ≤40%, significantly higher doses of beta blockers and ace inhibitors were prescribed after the clinic visit.

Conclusion: The HF MRTCC identified and corrected numerous medication discrepancies, up-titrated medications, and was associated with a 30-day readmission rate of 9%. These encouraging pilot results are hypothesis-generating and warrant further controlled trials.

Keywords: Heart failure; Medication reconciliation; Transition.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiovascular Agents / adverse effects
  • Cardiovascular Agents / therapeutic use*
  • Drug Dosage Calculations
  • Female
  • Heart Failure / diagnosis
  • Heart Failure / drug therapy*
  • Heart Failure / physiopathology
  • Humans
  • Inappropriate Prescribing
  • Leadership
  • Male
  • Medication Reconciliation / organization & administration*
  • Middle Aged
  • Patient Discharge*
  • Patient Readmission
  • Pharmacists / organization & administration*
  • Pharmacy Service, Hospital / organization & administration*
  • Physical Examination
  • Pilot Projects
  • Professional Role*
  • Program Evaluation
  • Quality Improvement / organization & administration
  • Quality Indicators, Health Care / organization & administration
  • Retrospective Studies
  • Time Factors
  • Transitional Care / organization & administration*

Substances

  • Cardiovascular Agents