Active prosthetic knees have the capability to provide net positive work, which is required in daily activities like stair and ramp negotiation or sit-to-stand transfers. Adding this capability might help to increase user mobility, safety, and independence. This article summarizes the biomechanical knee requirements for different activities of daily living and critically compares them with the actuator characteristics of state-of-the-art active prosthetic knee joints. As a result of a systematic literature research 22 active prosthetic knee joints were identified. Most systems use a stiff actuator in combination with a ball screw and are capable of supporting the majority of daily tasks for the average US citizen (82.5 kg) at self-selected movement speed. Physiological requirements exceed most system specifications if increased user mass, walking speed, or inclinations are assumed. To cope with the requirements, springs and dampers are used to assist the motor. The comparison of the prostheses characteristics with anthropometric data shows that most of the devices are in the physiological range for the system height and even when being tethered it is critical to achieve a physiological mass. Also while just one active knee is commercialized so far, physiological knee biomechanics show that there is a potential for active prosthetic knee solutions. Summarized biomechanical and anthropometric data can be used as a framework to develop prototypes. Further, the overview of state-of-the-art systems can provide possible solutions to deal with the task specific prosthetic knee requirements.