Residential greenness and allergic respiratory diseases in children and adolescents - A systematic review and meta-analysis

Environ Res. 2017 Nov:159:212-221. doi: 10.1016/j.envres.2017.08.002. Epub 2017 Aug 10.

Abstract

Background: The aetiology of allergic respiratory disease in children is not yet fully understood. Environmental factors are believed to play a major part. The amount of green vegetation surrounding the home (residential greenness) has been recently identified as a potentially important exposure OBJECTIVES: Our goal was to provide a systematic review and quantitative summary of the evidence regarding the relationship between residential greenness and allergic respiratory diseases in children.

Methods: Peer-reviewed literature published prior to 1 March 2017 was systematically searched using nine electronic databases. Meta-analyses were conducted if at least three studies published risk estimates for the same outcome and exposure measures.

Results: We included 11 articles across broad outcomes of asthma and allergic rhinitis. Reported effects were inconsistent with varying measures to define residential greenness. Only limited meta-analysis could be conducted, with the pooled odds ratios for asthma (OR 1.01 95%CI 0.93, 1.09; I2 68.1%) and allergic rhinitis (OR 0.99 95%CI 0.87, 1.12; I2 72.9%) being significantly heterogeneous.

Conclusions: Inconsistencies between the studies were too large to accurately assess the association between residential greenness and allergic respiratory disease. A standardised global measure of greenness which accounts for seasonal variation at a specific relevant buffer size is needed to create a more cohesive body of evidence and for future examination of the effect of residential greenness on allergic respiratory diseases.

Keywords: Allergic Rhinitis; Asthma; Greenness; LiDAR; NDVI; Paediatric.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Adolescent
  • Asthma / epidemiology*
  • Asthma / etiology
  • Child
  • Child, Preschool
  • Environment*
  • Housing
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Prevalence
  • Rhinitis, Allergic / epidemiology*
  • Rhinitis, Allergic / etiology