SnapShot: Cellular Senescence Pathways

Ricardo Iván Martínez-Zamudio; Lucas Robinson; Pierre-Francois Roux; Oliver Bischof

doi:10.1016/j.cell.2017.07.049

SnapShot: Cellular Senescence Pathways

Cell. 2017 Aug 10;170(4):816-816.e1. doi: 10.1016/j.cell.2017.07.049.

Authors

Ricardo Iván Martínez-Zamudio¹, Lucas Robinson¹, Pierre-Francois Roux¹, Oliver Bischof¹

Affiliation

¹ INSERM, U993, 75015 Paris, France; Equipe Labellisée Fondation ARC pour la recherche sur le cancer, 94803 Villejuif, France; Institut Pasteur, Molecular and Cellular Biology of Cellular Senescence and Age-Related Pathologies Group, Nuclear Organization and Oncogenesis Unit, Department of Cell Biology and Infection, 75015 Paris, France.

PMID: 28802049
DOI: 10.1016/j.cell.2017.07.049

Abstract

Cellular senescence is a fundamental cell fate, playing important physiological and pathophysiological roles. This SnapShot focuses on major signaling pathways and transcriptional control mechanisms that consolidate the senescence phenotype.

MeSH terms

Animals
Cell Cycle
Cellular Senescence*
Humans
Inflammation / immunology
Neoplasms / drug therapy