[Branch duct intraductal papillary mucinous neoplasm - surgical approach]

Chirurg. 2017 Nov;88(11):927-933. doi: 10.1007/s00104-017-0491-3.
[Article in German]

Abstract

Due to increasing precision of modern imaging modalities, intraductal papillary mucinous neoplasms (IPMN) of the pancreas are found with increasing prevalence. Despite their malignant potential IPMN are often kept under surveillance and are not immediately resected. The 2012 International Consensus Guidelines of Fukuoka have been widely accepted for the management of IPMN. They recommend surgical resection for branch duct IPMN with "high risk stigmata", while branch duct IPMN with "worrisome features" should undergo observation without immediate resection. Consequently, patients with asymptomatic branch duct IPMN and a presumed low malignant potential mostly undergo primary surveillance to avoid surgery-related morbidity and mortality following pancreatic resection; however, with respect to the cumulative risk of malignant transformation over time, surgical resection might also be indicated for patients with branch duct IPMN with "worrisome features". This article discusses the indications for surgery and different options of resection of branch duct IPMN.

Keywords: Branch duct IPMN; Fukuoka criteria; Indications; Observation; Parenchyma sparing resection.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma, Mucinous / pathology
  • Adenocarcinoma, Mucinous / surgery*
  • Adenocarcinoma, Papillary / pathology
  • Adenocarcinoma, Papillary / surgery*
  • Carcinoma, Pancreatic Ductal / pathology
  • Carcinoma, Pancreatic Ductal / surgery*
  • Cell Transformation, Neoplastic / pathology
  • Guideline Adherence
  • Humans
  • Pancreatectomy
  • Prognosis
  • Watchful Waiting