Update on Postdialysis Rebound by a New Technology in Hemodialysis

Ther Apher Dial. 2017 Oct;21(5):473-477. doi: 10.1111/1744-9987.12545. Epub 2017 Aug 9.

Abstract

After dialysis ends, urea continued movement causes rebound postdialysis, with values at about 20%. New techniques have been incorporated into hemodialysis, but their relationship with rebound has not yet been studied. This study aimed to quantify urea rebound at 30-min postdialysis during sessions using polysulfone filters and high-flow versus online hemodiafiltration, and to define its correlation with body composition measured by bioimpedance by a cross-sectional study with 69 patients (December 2015 to January 2016). Mean urea rebound was 24.39, which was positively associated with recirculation, Kt/V or hypotension, and showed a negative relationship with online hemodiafiltration. It was not associated with different body composition compartments. To conclude, postdialysis urea rebound remained high with polysulfone dialyzers and low dialysis doses. Online hemodiafiltration could improve postdialysis urea rebound. Different body composition compartments were not related to rebound.

Keywords: Body composition; Hemodiafiltration; Hemodialysis; Rebound; Urea.

MeSH terms

  • Aged
  • Body Composition
  • Cross-Sectional Studies
  • Electric Impedance
  • Female
  • Hemodiafiltration / instrumentation
  • Hemodiafiltration / methods*
  • Humans
  • Kidney Failure, Chronic / therapy*
  • Male
  • Membranes, Artificial
  • Middle Aged
  • Polymers / chemistry
  • Renal Dialysis / instrumentation
  • Renal Dialysis / methods*
  • Sulfones / chemistry
  • Time Factors
  • Urea / metabolism*

Substances

  • Membranes, Artificial
  • Polymers
  • Sulfones
  • polysulfone P 1700
  • Urea